The Egocentric Comorbidity Network on Tick-borne rickettsioses
Disease Info.
ICD-9:
082
Disease ID:
50
Disease Name:
Tick-borne rickettsioses
Descriptives of the sampled nested cases-control dataset
Total individual=
260
Case:Control =
52
:
208
( 1 :
4
)
No. of control with zero baseline=
141
No. of select variables=
98
Messages in th clogit procedure
WARN: Loglik converged before variable 1,2,3,4,5,6,7,8,9,10,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,77,78,79,80,81,87,88,89,90,91,92,94,95,96 ; coefficient may be infinite.
Fitted coefficients in conditional logistic model (Full table)
| coef | exp(coef) | se(coef) | z | Pr(>|z|) | name | sig |
|---|---|---|---|---|---|---|
| 584.092719 | 4.658486e+253 | 3.894983e+05 | 0.0014996 | 0.9988035 | Group B streptococcus infections of unspecified site | |
| 562.511727 | 1.975782e+244 | 4.449728e+05 | 0.0012641 | 0.9989914 | Other forms of chronic ischemic heart disease | |
| 535.946937 | 5.738484e+232 | 1.165972e+06 | 0.0004597 | 0.9996332 | Other and unspecified complications of the puerperium, not elsewhere classified | |
| 472.231647 | 1.223485e+205 | 6.798490e+05 | 0.0006946 | 0.9994458 | Chronic airways obstruction, not elsewhere classified | |
| 452.799753 | 4.450758e+196 | 2.768824e+05 | 0.0016354 | 0.9986952 | Mononeuritis of upper limb and mononeuritis multiplex | |
| 388.040915 | 3.342169e+168 | 3.638801e+05 | 0.0010664 | 0.9991491 | Cardiac dysrhythmias | |
| 308.132289 | 6.609258e+133 | 3.985806e+05 | 0.0007731 | 0.9993832 | Nerve root and plexus disorders | |
| 304.877877 | 2.551407e+132 | 3.103115e+05 | 0.0009825 | 0.9992161 | Early or threatened labor | |
| 264.447836 | 7.050757e+114 | 6.252701e+05 | 0.0004229 | 0.9996625 | Chronic bronchitis | |
| 260.375668 | 1.201478e+113 | 7.962808e+05 | 0.0003270 | 0.9997391 | Chronic ulcer of skin | |
| 232.212081 | 7.053838e+100 | 2.599995e+05 | 0.0008931 | 0.9992874 | Spondylosis and allied disorders | |
| 178.366065 | 2.906683e+77 | 2.793670e+05 | 0.0006385 | 0.9994906 | Noninflammatory disorders of cervix | |
| 114.638226 | 6.119966e+49 | 3.655398e+04 | 0.0031361 | 0.9974977 | Chronic pharyngitis and nasopharyngitis | |
| 94.339317 | 9.355025e+40 | 4.305542e+05 | 0.0002191 | 0.9998252 | Herpes simplex | |
| 91.539601 | 5.690409e+39 | 8.390329e+04 | 0.0010910 | 0.9991295 | Hemorrhage in early pregnancy | |
| 88.878872 | 3.977442e+38 | 4.131638e+04 | 0.0021512 | 0.9982836 | Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue | |
| 85.487284 | 1.338615e+37 | 6.636675e+04 | 0.0012881 | 0.9989722 | Other disorders of skin and subcutaneous tissue | |
| 76.110739 | 1.133637e+33 | 3.335614e+04 | 0.0022818 | 0.9981794 | Urticaria | |
| 75.038786 | 3.880884e+32 | 2.754732e+04 | 0.0027240 | 0.9978266 | Benign neoplasm of ovary | |
| 74.074165 | 1.479112e+32 | 1.895270e+05 | 0.0003908 | 0.9996882 | Other disorders of cervical region | |
| 64.580385 | 1.114050e+28 | 2.582147e+05 | 0.0002501 | 0.9998004 | Disorders of lacrimal system | |
| 56.896900 | 5.128726e+24 | 2.029020e+04 | 0.0028042 | 0.9977626 | Ankylosing spondylitis and other inflammatory spondylopathies | |
| 54.383492 | 4.153847e+23 | 4.090429e+04 | 0.0013295 | 0.9989392 | Other symptoms involving abdomen and pelvis | |
| 53.159015 | 1.220863e+23 | 2.297763e+04 | 0.0023135 | 0.9981541 | Normal delivery | |
| 52.401065 | 5.721282e+22 | 5.506855e+05 | 0.0000952 | 0.9999241 | Other disorders of liver | |
| 52.165579 | 4.520880e+22 | 7.736788e+04 | 0.0006743 | 0.9994620 | Gastric ulcer | |
| 48.214495 | 8.695394e+20 | 7.565918e+04 | 0.0006373 | 0.9994915 | Other disorders of breast | |
| 42.764927 | 3.737420e+18 | 4.252751e+05 | 0.0001006 | 0.9999198 | Excessive vomiting in pregnancy | |
| 42.675165 | 3.416558e+18 | 1.564135e+05 | 0.0002728 | 0.9997823 | Peptic ulcer, site unspecified | |
| 38.247458 | 4.079997e+16 | 1.687137e+04 | 0.0022670 | 0.9981912 | Diseases of sebaceous glands | |
| 35.577364 | 2.825223e+15 | 2.121488e+05 | 0.0001677 | 0.9998662 | Other and unspecified arthropathies | |
| 33.061805 | 2.283281e+14 | 1.042630e+05 | 0.0003171 | 0.9997470 | Other diseases of endocardium | |
| 28.789303 | 3.184456e+12 | 8.550047e+04 | 0.0003367 | 0.9997313 | Disorders of sweat glands | |
| 22.935657 | 9.137542e+09 | 5.564424e+05 | 0.0000412 | 0.9999671 | Other hypertrophic and atrophic conditions of skin | |
| 20.441201 | 7.542250e+08 | 6.279249e+03 | 0.0032554 | 0.9974026 | Duodenal ulcer | |
| 18.696718 | 1.317897e+08 | 4.548548e+04 | 0.0004110 | 0.9996720 | Disorders of tooth development and eruption | |
| 18.658071 | 1.267936e+08 | 4.110622e+04 | 0.0004539 | 0.9996378 | Pruritus and related conditions | |
| 18.649442 | 1.257042e+08 | 6.279249e+03 | 0.0029700 | 0.9976303 | General symptoms | |
| 18.336336 | 9.191142e+07 | 2.061063e+04 | 0.0008897 | 0.9992902 | Other diseases of upper respiratory tract | |
| 18.110371 | 7.332200e+07 | 2.841512e+04 | 0.0006373 | 0.9994915 | Dermatophytosis | |
| 14.797546 | 2.669885e+06 | 8.064409e+04 | 0.0001835 | 0.9998536 | Symptoms involving urinary system | |
| 14.116842 | 1.351658e+06 | 6.279250e+03 | 0.0022482 | 0.9982062 | Gingival and periodontal diseases | |
| 13.923403 | 1.113928e+06 | 3.319100e+05 | 0.0000419 | 0.9999665 | Symptoms involving skin and other integumentary tissue | |
| 10.312961 | 3.012049e+04 | 1.418610e+04 | 0.0007270 | 0.9994200 | Disorders of function of stomach | |
| 8.750420 | 6.313337e+03 | 2.177535e+04 | 0.0004018 | 0.9996794 | Symptoms involving head and neck | |
| 8.437314 | 4.616138e+03 | 6.858873e+03 | 0.0012301 | 0.9990185 | Asthma | |
| 8.164435 | 3.513737e+03 | 9.415920e+03 | 0.0008671 | 0.9993082 | Functional digestive disorders, not elsewhere classified | |
| 3.868468 | 4.786901e+01 | 2.515009e+05 | 0.0000154 | 0.9999877 | Chronic disease of tonsils and adenoids | |
| 1.791759 | 6.000000e+00 | 1.171929e+00 | 1.5288976 | 0.1262898 | Diseases of hard tissues of teeth | |
| 1.098612 | 3.000000e+00 | 1.102356e+00 | 0.9966034 | 0.3189570 | Disorders of refraction and accommodation | |
| 0.000000 | 1.000000e+00 | 4.067806e+05 | 0.0000000 | 1.0000000 | Symptoms involving cardiovascular system | |
| -4.823707 | 8.036900e-03 | 5.357501e+04 | -0.0000900 | 0.9999282 | Other and unspecified disorders of back | |
| -5.679529 | 3.415200e-03 | 9.415920e+03 | -0.0006032 | 0.9995187 | Benign neoplasm of skin | |
| -6.795086 | 1.119300e-03 | 6.858872e+03 | -0.0009907 | 0.9992095 | Other noninfectious gastroenteritis and colitis | |
| -7.744167 | 4.333000e-04 | 6.858873e+03 | -0.0011291 | 0.9990991 | Diseases of pulp and periapical tissues | |
| -15.215455 | 2.000000e-07 | 6.279249e+03 | -0.0024231 | 0.9980666 | Allergic rhinitis | |
| -16.385367 | 1.000000e-07 | 3.543126e+05 | -0.0000462 | 0.9999631 | Other and unspecified anemias | |
| -17.101721 | 0.000000e+00 | 1.982866e+04 | -0.0008625 | 0.9993118 | Other perinatal jaundice | |
| -17.733151 | 0.000000e+00 | 6.279249e+03 | -0.0028241 | 0.9977467 | Affective psychoses | |
| -19.242054 | 0.000000e+00 | 6.119454e+04 | -0.0003144 | 0.9997491 | Essential hypertension | |
| -22.258345 | 0.000000e+00 | 3.793105e+04 | -0.0005868 | 0.9995318 | Other current conditions in the mother classifiable elsewhere, but complicating pregnancy, childbirth, or the puerperium | |
| -22.668541 | 0.000000e+00 | 7.577984e+04 | -0.0002991 | 0.9997613 | Symptoms involving respiratory system and other chest symptoms | |
| -24.867370 | 0.000000e+00 | 1.160146e+05 | -0.0002143 | 0.9998290 | Suppurative and unspecified otitis media | |
| -30.201395 | 0.000000e+00 | 1.163577e+05 | -0.0002596 | 0.9997929 | Specific diseases due to Coxsackie virus | |
| -31.009589 | 0.000000e+00 | 1.603938e+04 | -0.0019333 | 0.9984574 | Contact dermatitis and other eczema | |
| -31.124056 | 0.000000e+00 | 1.255850e+04 | -0.0024783 | 0.9980226 | Inflammatory disease of cervix, vagina and vulva | |
| -32.894626 | 0.000000e+00 | 2.500929e+05 | -0.0001315 | 0.9998951 | Pain and other symptoms associated with female genital organs | |
| -41.140568 | 0.000000e+00 | 8.604858e+04 | -0.0004781 | 0.9996185 | Other derangement of joint | |
| -41.601704 | 0.000000e+00 | 3.242672e+04 | -0.0012829 | 0.9989764 | Other diseases due to viruses and Chlamydiae | |
| -44.097051 | 0.000000e+00 | 2.103565e+04 | -0.0020963 | 0.9983274 | Disorders of menstruation and other abnormal bleeding from female genital tract | |
| -45.546895 | 0.000000e+00 | 1.206248e+05 | -0.0003776 | 0.9996987 | Other diseases and conditions of the teeth and supporting structures | |
| -58.492014 | 0.000000e+00 | 3.402440e+05 | -0.0001719 | 0.9998628 | Herpes zoster | |
| -66.915868 | 0.000000e+00 | 4.253064e+04 | -0.0015734 | 0.9987446 | Other disorders of urethra and urinary tract | |
| -74.537346 | 0.000000e+00 | 4.133285e+05 | -0.0001803 | 0.9998561 | Diabetes mellitus | |
| -75.662959 | 0.000000e+00 | 1.111041e+05 | -0.0006810 | 0.9994566 | Osteoarthrosis and allied disorders | |
| -94.348523 | 0.000000e+00 | 4.325651e+05 | -0.0002181 | 0.9998260 | Noninflammatory disorders of ovary, fallopian tube and broad ligament | |
| -96.796798 | 0.000000e+00 | 4.484098e+05 | -0.0002159 | 0.9998278 | Chronic liver disease and cirrhosis | |
| -97.598009 | 0.000000e+00 | 6.382295e+04 | -0.0015292 | 0.9987799 | Intervertebral disc disorders | |
| -97.780544 | 0.000000e+00 | 3.395586e+04 | -0.0028796 | 0.9977024 | Gastritis and duodenitis | |
| -115.033487 | 0.000000e+00 | 9.680788e+04 | -0.0011883 | 0.9990519 | Other disorders of eyelids | |
| -119.133864 | 0.000000e+00 | 3.814812e+05 | -0.0003123 | 0.9997508 | Menopausal and postmenopausal disorders | |
| -181.398232 | 0.000000e+00 | 5.001501e+04 | -0.0036269 | 0.9971062 | Neurotic disorders | |
| -211.738571 | 0.000000e+00 | 2.607665e+05 | -0.0008120 | 0.9993521 | Migraine | |
| -213.202104 | 0.000000e+00 | 7.114376e+04 | -0.0029968 | 0.9976089 | Vertiginous syndromes and other disorders of vestibular system | |
| -265.399833 | 0.000000e+00 | 4.203280e+05 | -0.0006314 | 0.9994962 | Antepartum hemorrhage, abruptio placentae, and placenta previa | |
| -295.533368 | 0.000000e+00 | 1.159093e+06 | -0.0002550 | 0.9997966 | Other complications of pregnancy, not elsewhere classified | |
| -364.098745 | 0.000000e+00 | 3.535903e+05 | -0.0010297 | 0.9991784 | Hemorrhoids | |
| -593.864867 | 0.000000e+00 | 6.377244e+05 | -0.0009312 | 0.9992570 | Hypertensive heart disease | |
| -922.569541 | 0.000000e+00 | 7.320659e+05 | -0.0012602 | 0.9989945 | Angina pectoris | |
| NA | NA | 0.000000e+00 | NA | NA | Other and unspecified disorder of joint | |
| NA | NA | 0.000000e+00 | NA | NA | Peripheral enthesopathies and allied syndromes | |
| NA | NA | 0.000000e+00 | NA | NA | Other disorders of synovium, tendon and bursa | |
| NA | NA | 0.000000e+00 | NA | NA | Disorders of muscle, ligament and fascia | |
| NA | NA | 0.000000e+00 | NA | NA | Other disorders of soft tissues | |
| NA | NA | 0.000000e+00 | NA | NA | Other disorders of bone and cartilage | |
| NA | NA | 0.000000e+00 | NA | NA | Symptoms involving digestive system | |
| NA | NA | 0.000000e+00 | NA | NA | Dermatomycosis, other and unspecified | |
| NA | NA | 0.000000e+00 | NA | NA | Candidiasis |
Age distribution of cases
Prevalence of exposure in the dataset per 100,000
| case | control | overall | name |
|---|---|---|---|
| 46153.85 | 17307.69 | 23076.92 | Diseases of hard tissues of teeth |
| 34615.38 | 11538.46 | 16153.85 | General symptoms |
| 26923.08 | 14423.08 | 16923.08 | Gingival and periodontal diseases |
| 25000.00 | 8173.08 | 11538.46 | Other symptoms involving abdomen and pelvis |
| 23076.92 | 11538.46 | 13846.15 | Gastritis and duodenitis |
| 23076.92 | 8653.85 | 11538.46 | Other noninfectious gastroenteritis and colitis |
| 23076.92 | 7692.31 | 10769.23 | Inflammatory disease of cervix, vagina and vulva |
| 21153.85 | 11057.69 | 13076.92 | Contact dermatitis and other eczema |
| 17307.69 | 7692.31 | 9615.38 | Functional digestive disorders, not elsewhere classified |
| 17307.69 | 9134.62 | 10769.23 | Disorders of menstruation and other abnormal bleeding from female genital tract |
| 17307.69 | 10576.92 | 11923.08 | Symptoms involving head and neck |
| 17307.69 | 5288.46 | 7692.31 | Symptoms involving respiratory system and other chest symptoms |
| 13461.54 | 4807.69 | 6538.46 | Disorders of refraction and accommodation |
| 13461.54 | 4326.92 | 6153.85 | Diseases of sebaceous glands |
| 13461.54 | 4807.69 | 6538.46 | Urticaria |
| 13461.54 | 4326.92 | 6153.85 | Dermatophytosis |
| 11538.46 | 6250.00 | 7307.69 | Allergic rhinitis |
| 11538.46 | 6730.77 | 7692.31 | Disorders of function of stomach |
| 11538.46 | 5288.46 | 6538.46 | Pruritus and related conditions |
| 11538.46 | 4326.92 | 5769.23 | Osteoarthrosis and allied disorders |
| 11538.46 | 3365.38 | 5000.00 | Other disorders of synovium, tendon and bursa |
| 11538.46 | 7692.31 | 8461.54 | Other disorders of soft tissues |
| 9615.38 | 1923.08 | 3461.54 | Peptic ulcer, site unspecified |
| 9615.38 | 2884.62 | 4230.77 | Other and unspecified disorder of joint |
| 7692.31 | 961.54 | 2307.69 | Benign neoplasm of skin |
| 7692.31 | 1442.31 | 2692.31 | Asthma |
| 7692.31 | 6730.77 | 6923.08 | Diseases of pulp and periapical tissues |
| 7692.31 | 5769.23 | 6153.85 | Other and unspecified disorders of back |
| 7692.31 | 4807.69 | 5384.62 | Symptoms involving digestive system |
| 5769.23 | 2884.62 | 3461.54 | Neurotic disorders |
| 5769.23 | 961.54 | 1923.08 | Migraine |
| 5769.23 | 2403.85 | 3076.92 | Suppurative and unspecified otitis media |
| 5769.23 | 2403.85 | 3076.92 | Vertiginous syndromes and other disorders of vestibular system |
| 5769.23 | 3846.15 | 4230.77 | Essential hypertension |
| 5769.23 | 2403.85 | 3076.92 | Chronic bronchitis |
| 5769.23 | 6250.00 | 6153.85 | Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue |
| 5769.23 | 961.54 | 1923.08 | Duodenal ulcer |
| 5769.23 | 4326.92 | 4615.38 | Other disorders of urethra and urinary tract |
| 5769.23 | 3365.38 | 3846.15 | Other and unspecified arthropathies |
| 5769.23 | 3365.38 | 3846.15 | Peripheral enthesopathies and allied syndromes |
| 3846.15 | 1442.31 | 1923.08 | Benign neoplasm of ovary |
| 3846.15 | 961.54 | 1538.46 | Diabetes mellitus |
| 3846.15 | 1442.31 | 1923.08 | Hypertensive heart disease |
| 3846.15 | 2403.85 | 2692.31 | Other forms of chronic ischemic heart disease |
| 3846.15 | 3365.38 | 3461.54 | Chronic pharyngitis and nasopharyngitis |
| 3846.15 | 4326.92 | 4230.77 | Other diseases of upper respiratory tract |
| 3846.15 | 1923.08 | 2307.69 | Disorders of tooth development and eruption |
| 3846.15 | 2403.85 | 2692.31 | Other diseases and conditions of the teeth and supporting structures |
| 3846.15 | 480.77 | 1153.85 | Gastric ulcer |
| 3846.15 | 2884.62 | 3076.92 | Other disorders of breast |
| 3846.15 | 4326.92 | 4230.77 | Menopausal and postmenopausal disorders |
| 3846.15 | 1923.08 | 2307.69 | Hemorrhage in early pregnancy |
| 3846.15 | 1442.31 | 1923.08 | Excessive vomiting in pregnancy |
| 3846.15 | 480.77 | 1153.85 | Other complications of pregnancy, not elsewhere classified |
| 3846.15 | 961.54 | 1538.46 | Normal delivery |
| 3846.15 | 961.54 | 1538.46 | Disorders of sweat glands |
| 3846.15 | 480.77 | 1153.85 | Chronic ulcer of skin |
| 3846.15 | 1923.08 | 2307.69 | Other derangement of joint |
| 3846.15 | 1923.08 | 2307.69 | Other disorders of bone and cartilage |
| 3846.15 | 2403.85 | 2692.31 | Candidiasis |
| 1923.08 | 1923.08 | 1923.08 | Other and unspecified anemias |
| 1923.08 | 480.77 | 769.23 | Affective psychoses |
| 1923.08 | 480.77 | 769.23 | Group B streptococcus infections of unspecified site |
| 1923.08 | 480.77 | 769.23 | Nerve root and plexus disorders |
| 1923.08 | 480.77 | 769.23 | Mononeuritis of upper limb and mononeuritis multiplex |
| 1923.08 | 1923.08 | 1923.08 | Other disorders of eyelids |
| 1923.08 | 480.77 | 769.23 | Disorders of lacrimal system |
| 1923.08 | 961.54 | 1153.85 | Herpes zoster |
| 1923.08 | 961.54 | 1153.85 | Angina pectoris |
| 1923.08 | 1442.31 | 1538.46 | Herpes simplex |
| 1923.08 | 480.77 | 769.23 | Other diseases of endocardium |
| 1923.08 | 1442.31 | 1538.46 | Cardiac dysrhythmias |
| 1923.08 | 2884.62 | 2692.31 | Hemorrhoids |
| 1923.08 | 961.54 | 1153.85 | Chronic disease of tonsils and adenoids |
| 1923.08 | 480.77 | 769.23 | Chronic airways obstruction, not elsewhere classified |
| 1923.08 | 1442.31 | 1538.46 | Specific diseases due to Coxsackie virus |
| 1923.08 | 3365.38 | 3076.92 | Chronic liver disease and cirrhosis |
| 1923.08 | 480.77 | 769.23 | Other disorders of liver |
| 1923.08 | 2884.62 | 2692.31 | Other diseases due to viruses and Chlamydiae |
| 1923.08 | 961.54 | 1153.85 | Noninflammatory disorders of ovary, fallopian tube and broad ligament |
| 1923.08 | 961.54 | 1153.85 | Noninflammatory disorders of cervix |
| 1923.08 | 961.54 | 1153.85 | Pain and other symptoms associated with female genital organs |
| 1923.08 | 480.77 | 769.23 | Antepartum hemorrhage, abruptio placentae, and placenta previa |
| 1923.08 | 480.77 | 769.23 | Early or threatened labor |
| 1923.08 | 480.77 | 769.23 | Other current conditions in the mother classifiable elsewhere, but complicating pregnancy, childbirth, or the puerperium |
| 1923.08 | 480.77 | 769.23 | Other and unspecified complications of the puerperium, not elsewhere classified |
| 1923.08 | 480.77 | 769.23 | Other hypertrophic and atrophic conditions of skin |
| 1923.08 | 3365.38 | 3076.92 | Other disorders of skin and subcutaneous tissue |
| 1923.08 | 480.77 | 769.23 | Ankylosing spondylitis and other inflammatory spondylopathies |
| 1923.08 | 2884.62 | 2692.31 | Spondylosis and allied disorders |
| 1923.08 | 961.54 | 1153.85 | Intervertebral disc disorders |
| 1923.08 | 2884.62 | 2692.31 | Other disorders of cervical region |
| 1923.08 | 961.54 | 1153.85 | Disorders of muscle, ligament and fascia |
| 1923.08 | 480.77 | 769.23 | Other perinatal jaundice |
| 1923.08 | 1923.08 | 1923.08 | Symptoms involving skin and other integumentary tissue |
| 1923.08 | 1442.31 | 1538.46 | Symptoms involving cardiovascular system |
| 1923.08 | 3365.38 | 3076.92 | Symptoms involving urinary system |
| 1923.08 | 480.77 | 769.23 | Dermatomycosis, other and unspecified |