The Egocentric Comorbidity Network on Malignant neoplasm of bone and articular cartilage


Disease Info.
ICD-9: 170
Disease ID: 117
Disease Name: Malignant neoplasm of bone and articular cartilage
Descriptives of the sampled nested cases-control dataset
Total individual= 995
Case:Control = 199 : 796 ( 1 : 4 )
No. of control with zero baseline= 363
No. of select variables= 263
Messages in th clogit procedure
WARN: Loglik converged before variable 3,8,54,81,84,123,163,169,176,220 ; coefficient may be infinite.
Fitted coefficients in conditional logistic model (p<0.05 only)
*Progression links allowed are marked in red
coef exp(coef) se(coef) z Pr(>|z|) name sig
23.781 2.127304e+10 7.900 3.010 0.003 Deficiency of B -complex components **
16.325 1.229334e+07 8.009 2.038 0.042 Disorders of adrenal glands *
14.161 1.413313e+06 5.861 2.416 0.016 Deviated nasal septum *
10.124 2.492527e+04 4.286 2.362 0.018 Other endocrine disorders *
9.954 2.102613e+04 3.788 2.628 0.009 Hypotension **
9.792 1.788577e+04 3.456 2.833 0.005 Acute reaction to stress **
8.809 6.692300e+03 2.661 3.311 0.001 Diseases of the jaws ***
8.285 3.963874e+03 4.075 2.033 0.042 Other diseases of lung *
6.963 1.056821e+03 3.024 2.302 0.021 Other disorders of bladder *
5.953 3.847400e+02 2.737 2.175 0.030 Ankylosing spondylitis and other inflammatory spondylopathies *
5.808 3.329230e+02 2.546 2.281 0.023 Other malignant neoplasm of skin *
5.132 1.693110e+02 2.546 2.016 0.044 Varicose veins of lower extremities *
3.101 2.222400e+01 0.847 3.660 0.000 Neoplasm of unspecified nature ***
2.850 1.729000e+01 1.200 2.374 0.018 Other diseases of upper respiratory tract *
2.785 1.620500e+01 0.844 3.298 0.001 Disorders of refraction and accommodation ***
2.492 1.208600e+01 1.166 2.138 0.033 Benign neoplasm of skin *
2.028 7.596000e+00 0.938 2.162 0.031 Secondary malignant neoplasm of other specified sites *
1.795 6.020000e+00 0.701 2.560 0.010 Other and unspecified disorder of joint **
1.710 5.528000e+00 0.565 3.028 0.002 Contact dermatitis and other eczema **
1.699 5.467000e+00 0.582 2.921 0.003 Other disorders of soft tissues **
1.554 4.731000e+00 0.677 2.296 0.022 Functional digestive disorders, not elsewhere classified *
-1.482 2.270000e-01 0.617 -2.402 0.016 Symptoms involving respiratory system and other chest symptoms *
-2.106 1.220000e-01 0.674 -3.124 0.002 Other noninfectious gastroenteritis and colitis **
-2.209 1.100000e-01 0.669 -3.301 0.001 Gingival and periodontal diseases ***
-2.870 5.700000e-02 1.338 -2.145 0.032 Suppurative and unspecified otitis media *
-2.967 5.100000e-02 0.930 -3.191 0.001 Peripheral enthesopathies and allied syndromes ***
-3.226 4.000000e-02 1.130 -2.856 0.004 Dermatophytosis **
-3.436 3.200000e-02 1.241 -2.769 0.006 Cataract **
-3.723 2.400000e-02 1.791 -2.078 0.038 Symptoms involving urinary system *
-4.234 1.400000e-02 2.147 -1.972 0.049 Nephritis and nephropathy, not specified as acute or chronic *
-5.003 7.000000e-03 2.184 -2.291 0.022 Group B streptococcus infections of unspecified site *
-5.239 5.000000e-03 2.061 -2.542 0.011 Cardiac dysrhythmias *
-6.134 2.000000e-03 2.376 -2.581 0.010 Disorders of uterus, not elsewhere classified **
-7.729 0.000000e+00 3.571 -2.165 0.030 Hereditary and idiopathic peripheral neuropathy *
-7.914 0.000000e+00 3.279 -2.414 0.016 Other diseases of respiratory system *
Age distribution of cases
Prevalence of exposure in the dataset per 100,000
*marked green when case > control
case control overall name
57286.43 31532.66 36683.42 General symptoms
56281.41 25628.14 31758.79 Other and unspecified disorders of back
53768.84 31281.41 35778.89 Gingival and periodontal diseases
51758.79 28894.47 33467.34 Diseases of hard tissues of teeth
50753.77 23743.72 29145.73 Other disorders of soft tissues
37688.44 19849.25 23417.09 Osteoarthrosis and allied disorders
35678.39 20603.02 23618.09 Symptoms involving respiratory system and other chest symptoms
35175.88 22989.95 25427.14 Gastritis and duodenitis
35175.88 21105.53 23919.60 Contact dermatitis and other eczema
34673.37 19095.48 22211.06 Functional digestive disorders, not elsewhere classified
33668.34 20100.50 22814.07 Other symptoms involving abdomen and pelvis
32160.80 20603.02 22914.57 Essential hypertension
32160.80 19849.25 22311.56 Symptoms involving head and neck
30653.27 17462.31 20100.50 Inflammatory disease of cervix, vagina and vulva
29648.24 19723.62 21708.54 Disorders of function of stomach
29648.24 10175.88 14070.35 Other disorders of bone and cartilage
29145.73 17462.31 19798.99 Other and unspecified disorder of joint
28643.22 16708.54 19095.48 Other noninfectious gastroenteritis and colitis
28643.22 13442.21 16482.41 Spondylosis and allied disorders
27135.68 17587.94 19497.49 Diseases of pulp and periapical tissues
26633.17 14824.12 17185.93 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
24623.12 16080.40 17788.94 Neurotic disorders
23115.58 11432.16 13768.84 Disorders of menstruation and other abnormal bleeding from female genital tract
22613.07 14321.61 15979.90 Other disorders of urethra and urinary tract
22613.07 11432.16 13668.34 Other disorders of synovium, tendon and bursa
20100.50 14070.35 15276.38 Peptic ulcer, site unspecified
18592.96 125.63 3819.10 Secondary malignant neoplasm of other specified sites
18592.96 16582.91 16984.92 Disorders of lipoid metabolism
18592.96 9296.48 11155.78 Symptoms involving digestive system
18090.45 14321.61 15075.38 Cataract
18090.45 11432.16 12763.82 Pruritus and related conditions
17587.94 9547.74 11155.78 Other and unspecified arthropathies
17085.43 12185.93 13165.83 Allergic rhinitis
17085.43 6407.04 8542.71 Intervertebral disc disorders
16582.91 628.14 3819.10 Malignant neoplasm of female breast
16582.91 11180.90 12261.31 Menopausal and postmenopausal disorders
16582.91 9924.62 11256.28 Urticaria
16080.40 12939.70 13567.84 Peripheral enthesopathies and allied syndromes
14572.86 12311.56 12763.82 Diabetes mellitus
14070.35 10804.02 11457.29 Chronic liver disease and cirrhosis
14070.35 6030.15 7638.19 Disorders of muscle, ligament and fascia
13567.84 7160.80 8442.21 Other diseases and conditions of the teeth and supporting structures
12562.81 1758.79 3919.60 Neoplasm of unspecified nature
12562.81 5276.38 6733.67 Disorders of refraction and accommodation
12562.81 4396.98 6030.15 Other disorders of breast
12060.30 9798.99 10251.26 Vertiginous syndromes and other disorders of vestibular system
12060.30 3894.47 5527.64 Diseases of sebaceous glands
11557.79 8793.97 9346.73 Chronic pharyngitis and nasopharyngitis
11055.28 4899.50 6130.65 Other and unspecified anemias
10552.76 2512.56 4120.60 Benign neoplasm of skin
10552.76 11557.79 11356.78 Hypertensive heart disease
10050.25 5778.89 6633.17 Disorders of lacrimal system
10050.25 4773.87 5829.15 Other disorders of skin and subcutaneous tissue
10050.25 7914.57 8341.71 Dermatophytosis
9547.74 9547.74 9547.74 Other forms of chronic ischemic heart disease
9045.23 6281.41 6834.17 Visual disturbances
9045.23 4648.24 5527.64 Other diseases of upper respiratory tract
9045.23 5527.64 6231.16 Symptoms involving skin and other integumentary tissue
8542.71 376.88 2010.05 Malignant neoplasm of trachea, bronchus and lung
8542.71 6658.29 7035.18 Chronic bronchitis
8542.71 6030.15 6532.66 Gastric ulcer
8542.71 4773.87 5527.64 Other disorders of cervical region
8040.20 3015.08 4020.10 Hemorrhoids
7537.69 5778.89 6130.65 Asthma
7537.69 6783.92 6934.67 Diseases of esophagus
7537.69 7035.18 7135.68 Symptoms involving cardiovascular system
7035.18 3768.84 4422.11 Other disorders of eyelids
7035.18 4145.73 4723.62 Other disorders of ear
6532.66 4522.61 4924.62 Gout
6532.66 3768.84 4321.61 Special symptoms or syndromes not elsewhere classified
6532.66 3894.47 4422.11 Other disorders of eye
6532.66 4899.50 5226.13 Symptoms involving urinary system
6532.66 4522.61 4924.62 Candidiasis
6030.15 3643.22 4120.60 Uterine leiomyoma
6030.15 2386.93 3115.58 Affective psychoses
6030.15 2889.45 3517.59 Nerve root and plexus disorders
6030.15 4145.73 4522.61 Other retinal disorders
5527.64 125.63 1206.03 Secondary malignant neoplasm of respiratory and digestive systems
5527.64 3266.33 3718.59 Migraine
5527.64 3266.33 3718.59 Mononeuritis of upper limb and mononeuritis multiplex
5527.64 2261.31 2914.57 Chronic sinusitis
5527.64 3140.70 3618.09 Pain and other symptoms associated with female genital organs
5025.13 251.26 1206.03 Secondary and unspecified malignant neoplasm of lymph nodes
5025.13 2010.05 2613.07 Herpes zoster
5025.13 3517.59 3819.10 Duodenal ulcer
5025.13 4271.36 4422.11 Other diseases due to viruses and Chlamydiae
4522.61 1130.65 1809.05 Other benign neoplasm of connective and other soft tissue
4522.61 4020.10 4120.60 Physiological malfunction arising from mental factors
4522.61 2135.68 2613.07 Suppurative and unspecified otitis media
4522.61 2889.45 3216.08 Other diseases of endocardium
4522.61 6783.92 6331.66 Cardiac dysrhythmias
4522.61 3643.22 3819.10 Heart failure
4522.61 3140.70 3417.09 Noninflammatory disorders of vagina
4020.10 2261.31 2613.07 Iron deficiency anemias
4020.10 879.40 1507.54 Inflammatory and toxic neuropathy
4020.10 1507.54 2010.05 Hearing loss
4020.10 2261.31 2613.07 Chronic airways obstruction, not elsewhere classified
4020.10 3266.33 3417.09 Viral hepatitis
3517.59 879.40 1407.04 Benign neoplasm of other parts of digestive system
3517.59 251.26 904.52 Benign neoplasm of other and unspecified sites
3517.59 1005.03 1507.54 Depressive disorder, not elsewhere classified
3517.59 2135.68 2412.06 Ill-defined descriptions and complications of heart disease
3517.59 1758.79 2110.55 Late effects of cerebrovascular disease
3517.59 502.51 1105.53 Varicose veins of lower extremities
3517.59 628.14 1206.03 Noninflammatory disorders of ovary, fallopian tube and broad ligament
3517.59 2010.05 2311.56 Rheumatoid arthritis and other inflammatory polyarthropathies
3015.08 3266.33 3216.08 Glaucoma
3015.08 3266.33 3216.08 Angina pectoris
3015.08 1507.54 1809.05 Herpes simplex
3015.08 1256.28 1608.04 Other disorders of intestine
3015.08 1507.54 1809.05 Endometriosis
3015.08 3015.08 3015.08 Noninflammatory disorders of cervix
3015.08 3266.33 3216.08 Atopic dermatitis and related conditions
3015.08 879.40 1306.53 Dermatitis due to substances taken internally
3015.08 1884.42 2110.55 Diffuse diseases of connective tissue
2512.56 251.26 703.52 Other malignant neoplasm of skin
2512.56 251.26 703.52 Malignant neoplasm of thyroid gland
2512.56 753.77 1105.53 Nontoxic nodular goiter
2512.56 2010.05 2110.55 Thyrotoxicosis with or without goiter
2512.56 1256.28 1507.54 Other disorders of thyroid
2512.56 753.77 1105.53 Other extrapyramidal disease and abnormal movement disorders
2512.56 1256.28 1507.54 Group B streptococcus infections of unspecified site
2512.56 251.26 703.52 Myoneural disorders
2512.56 1256.28 1507.54 Corneal opacity and other disorders of cornea
2512.56 3015.08 2914.57 Other and ill-defined cerebrovascular disease
2512.56 502.51 904.52 Other venous embolism and thrombosis
2512.56 1005.03 1306.53 Dentofacial anomalies, including malocclusion
2512.56 879.40 1206.03 Nephritis and nephropathy, not specified as acute or chronic
2512.56 753.77 1105.53 Chronic renal failure
2512.56 1005.03 1306.53 Diseases of hair and hair follicles
2512.56 376.88 804.02 Chronic ulcer of skin
2512.56 753.77 1105.53 Symptoms involving nervous and musculoskeletal systems
2512.56 753.77 1105.53 Other ill-defined and unknown causes of morbidity and mortality
2010.05 502.51 804.02 Lipoma
2010.05 2010.05 2010.05 Benign neoplasm of breast
2010.05 1130.65 1306.53 Other benign neoplasm of uterus
2010.05 1005.03 1206.03 Benign neoplasm of ovary
2010.05 879.40 1105.53 Acquired hypothyroidism
2010.05 376.88 703.52 Pulmonary tuberculosis
2010.05 125.63 502.51 Other diseases of blood and blood-forming organs
2010.05 1758.79 1809.05 Senile and presenile organic psychotic conditions
2010.05 376.88 703.52 Adjustment reaction
2010.05 502.51 804.02 Epilepsy
2010.05 1507.54 1608.04 Nonsuppurative otitis media and eustachian tube disorders
2010.05 628.14 904.52 Other diseases of lung
2010.05 502.51 804.02 Regional enteritis
2010.05 2386.93 2311.56 Other disorders of liver
2010.05 753.77 1005.03 Nephrotic syndrome
2010.05 879.40 1105.53 Other disorders of bladder
2010.05 1884.42 1909.55 Hemorrhage in early pregnancy
2010.05 1130.65 1306.53 Erythematosquamous dermatosis
2010.05 628.14 904.52 Erythematous conditions
2010.05 1005.03 1206.03 Other hypertrophic and atrophic conditions of skin
2010.05 1758.79 1809.05 Disorders of sweat glands
2010.05 1256.28 1407.04 Other derangement of joint
2010.05 376.88 703.52 Osteomyelitis,periostitis and other infections involving bone
2010.05 376.88 703.52 Curvature of spine
2010.05 1507.54 1608.04 Other acquired deformity
1507.54 125.63 402.01 Malignant neoplasm of cervix uteri
1507.54 251.26 502.51 Benign neoplasm of respiratory and intrathoracic organs
1507.54 125.63 402.01 Benign neoplasm of brain and other parts of nervous system
1507.54 251.26 502.51 Neoplasm of uncertain behavior of other and unspecified sites and tissues
1507.54 1256.28 1306.53 Simple and unspecified goiter
1507.54 376.88 603.02 Purpura and other hemorrhagic conditions
1507.54 376.88 603.02 Acute reaction to stress
1507.54 251.26 502.51 Other cerebral degenerations
1507.54 1381.91 1407.04 Parkinson's disease
1507.54 1005.03 1105.53 Other paralytic syndromes
1507.54 1381.91 1407.04 Mononeuritis of lower limb
1507.54 753.77 904.52 Disorders of optic nerve and visual pathways
1507.54 1758.79 1708.54 Other peripheral vascular disease
1507.54 753.77 904.52 Bronchiectasis
1507.54 125.63 402.01 Disorders of tooth development and eruption
1507.54 753.77 904.52 Diseases of the salivary glands
1507.54 125.63 402.01 Abscess of anal and rectal regions
1507.54 628.14 804.02 Chronic glomerulonephritis
1507.54 1005.03 1105.53 Other disorders of kidney and ureter
1507.54 1005.03 1105.53 Other disorders of female genital organs
1507.54 125.63 402.01 Psoriasis and similar disorders
1507.54 628.14 804.02 Other dermatoses
1507.54 1507.54 1507.54 Internal derangement of knee
1507.54 628.14 804.02 Ankylosing spondylitis and other inflammatory spondylopathies
1507.54 502.51 703.52 Late effects of tuberculosis
1507.54 125.63 402.01 Malignant neoplasm of nasopharynx
1005.03 502.51 603.02 Malignant neoplasm of colon
1005.03 125.63 301.51 Malignant neoplasm of rectum, rectosigmoid junction, and anus
1005.03 251.26 402.01 Malignant neoplasm of kidney and other and unspecified urinary organs
1005.03 125.63 301.51 Benign neoplasm of eye
1005.03 125.63 301.51 Hemangioma and lymphangioma, any site
1005.03 502.51 603.02 Disorders of the pituitary gland and its hypothalamic control
1005.03 251.26 402.01 Disorders of adrenal glands
1005.03 125.63 301.51 Diseases of white blood cells
1005.03 251.26 402.01 Hemiplegia and hemiparesis
1005.03 1256.28 1206.03 Hereditary and idiopathic peripheral neuropathy
1005.03 251.26 402.01 Other disorders of tympanic membrane
1005.03 125.63 301.51 Other disorders of middle ear and mastoid
1005.03 125.63 301.51 Chickenpox
1005.03 376.88 502.51 Hypertensive renal disease
1005.03 251.26 402.01 Hypotension
1005.03 502.51 603.02 Other disorders of circulatory system
1005.03 1381.91 1306.53 Other diseases of respiratory system
1005.03 125.63 301.51 Diseases of the jaws
1005.03 502.51 603.02 Diseases and other conditions of the tongue
1005.03 753.77 804.02 Benign mammary dysplasias
1005.03 628.14 703.52 Disorders of uterus, not elsewhere classified
1005.03 125.63 301.51 Antepartum hemorrhage, abruptio placentae, and placenta previa
1005.03 376.88 502.51 Other congenital musculoskeletal anomalies
1005.03 1130.65 1105.53 Nonspecific findings on examination of blood
1005.03 879.40 904.52 Dermatomycosis, other and unspecified
502.51 502.51 502.51 Malignant neoplasm of liver and intrahepatic bile ducts
502.51 376.88 402.01 Benign neoplasm of lip, oral cavity and pharynx
502.51 376.88 402.01 Carcinoma in situ of breast and genitourinary system
502.51 753.77 703.52 Thyroiditis
502.51 376.88 402.01 Ovarian dysfunction
502.51 376.88 402.01 Other endocrine disorders
502.51 251.26 301.51 Other and unspecified protein-calorie malnutrition
502.51 125.63 201.01 Deficiency of B -complex components
502.51 251.26 301.51 Other deficiency anemias
502.51 251.26 301.51 Coagulation defects
502.51 125.63 201.01 Other organic psychotic conditions (chronic)
502.51 125.63 201.01 Schizophrenic disorders
502.51 251.26 301.51 Disorders of the autonomic nervous system
502.51 376.88 402.01 Infantile cerebral palsy
502.51 753.77 703.52 Facial nerve disorders
502.51 125.63 201.01 Muscular dystrophies and other myopathies
502.51 753.77 703.52 Disorders of the globe
502.51 376.88 402.01 Retinal detachments and defects
502.51 251.26 301.51 Disorders of iris and ciliary body
502.51 376.88 402.01 Rheumatic diseases of aortic valve
502.51 125.63 201.01 Other rheumatic heart disease
502.51 502.51 502.51 Secondary hypertension
502.51 628.14 603.02 Coronary occlusion without myocardial infarction
502.51 1130.65 1005.03 Acute, but ill-defined, cerebrovascular disease
502.51 1381.91 1206.03 Atherosclerosis
502.51 251.26 301.51 Arterial embolism and thrombosis
502.51 125.63 201.01 Polyarteritis nodosa and allied conditions
502.51 502.51 502.51 Other disorders of arteries and arterioles
502.51 251.26 301.51 Varicose veins of other sites
502.51 251.26 301.51 Deviated nasal septum
502.51 251.26 301.51 Nasal polyps
502.51 628.14 603.02 Gastrojejunal ulcer
502.51 628.14 603.02 Diverticula of intestine
502.51 125.63 201.01 Specific diseases due to Coxsackie virus
502.51 251.26 301.51 Liver abscess and sequelae of chronic liver disease
502.51 502.51 502.51 Acute renal failure
502.51 879.40 804.02 Hydronephrosis
502.51 628.14 603.02 Genital prolapse
502.51 376.88 402.01 Excessive vomiting in pregnancy
502.51 125.63 201.01 Other complications of pregnancy, not elsewhere classified
502.51 125.63 201.01 Normal delivery
502.51 251.26 301.51 Abnormality of organs and soft tissues of pelvis
502.51 125.63 201.01 Other fetal and placental problems affecting management of mother
502.51 125.63 201.01 Other complications of labor and delivery, not elsewhere classified
502.51 376.88 402.01 Corns and callosities
502.51 125.63 201.01 Arthropathy associated with infections
502.51 125.63 201.01 Crystal arthropathies
502.51 376.88 402.01 Arthropathy associated with other disorders classified elsewhere
502.51 251.26 301.51 Polymyalgia rheumatica
502.51 125.63 201.01 Congenital anomalies of urinary system
502.51 502.51 502.51 Nonspecific findings on examination of urine
502.51 879.40 804.02 Nonspecific abnormal results of function studies
502.51 251.26 301.51 Other mycoses
502.51 753.77 703.52 Acariasis