The Egocentric Comorbidity Network on Polyglandular dysfunction and related disorders


Disease Info.
ICD-9: 258
Disease ID: 199
Disease Name: Polyglandular dysfunction and related disorders
Descriptives of the sampled nested cases-control dataset
Total individual= 2090
Case:Control = 418 : 1672 ( 1 : 4 )
No. of control with zero baseline= 1029
No. of select variables= 280
Messages in th clogit procedure
:
Fitted coefficients in conditional logistic model (p<0.05 only)
*Progression links allowed are marked in red
coef exp(coef) se(coef) z Pr(>|z|) name sig
2.258 9.561 0.928 2.432 0.015 Disorders of adrenal glands *
1.972 7.181 0.949 2.078 0.038 Rheumatoid arthritis and other inflammatory polyarthropathies *
1.816 6.150 0.770 2.361 0.018 Glaucoma *
1.408 4.088 0.701 2.008 0.045 Other and ill-defined cerebrovascular disease *
1.167 3.214 0.457 2.556 0.011 Acquired hypothyroidism *
1.015 2.760 0.393 2.581 0.010 Simple and unspecified goiter **
0.989 2.689 0.213 4.637 0.000 Diseases of hard tissues of teeth ***
0.847 2.332 0.286 2.966 0.003 Other endocrine disorders **
0.820 2.271 0.226 3.622 0.000 Pain and other symptoms associated with female genital organs ***
0.773 2.166 0.304 2.538 0.011 Disorders of tooth development and eruption *
0.595 1.813 0.174 3.412 0.001 Symptoms involving respiratory system and other chest symptoms ***
0.557 1.745 0.184 3.030 0.002 Disorders of menstruation and other abnormal bleeding from female genital tract **
0.505 1.656 0.168 3.005 0.003 Disorders of function of stomach **
0.460 1.584 0.198 2.324 0.020 Chronic pharyngitis and nasopharyngitis *
0.418 1.519 0.197 2.123 0.034 Diseases of sebaceous glands *
-0.469 0.625 0.233 -2.014 0.044 Other diseases of upper respiratory tract *
-0.732 0.481 0.294 -2.489 0.013 Other disorders of breast *
-0.819 0.441 0.414 -1.978 0.048 Benign neoplasm of skin *
-1.280 0.278 0.559 -2.289 0.022 Other hypertrophic and atrophic conditions of skin *
-1.326 0.266 0.545 -2.432 0.015 Noninflammatory disorders of ovary, fallopian tube and broad ligament *
-1.881 0.152 0.956 -1.969 0.049 Ankylosing spondylitis and other inflammatory spondylopathies *
-1.882 0.152 0.885 -2.126 0.033 Diffuse diseases of connective tissue *
-4.044 0.018 2.054 -1.969 0.049 Carcinoma in situ of breast and genitourinary system *
Age distribution of cases
Prevalence of exposure in the dataset per 100,000
*marked green when case > control
case control overall name
75598.09 24880.38 35023.92 Diseases of hard tissues of teeth
71531.10 23803.83 33349.28 Gingival and periodontal diseases
56937.80 14653.11 23110.05 Disorders of menstruation and other abnormal bleeding from female genital tract
51674.64 16028.71 23157.89 General symptoms
49043.06 15430.62 22153.11 Contact dermatitis and other eczema
48803.83 15191.39 21913.88 Other symptoms involving abdomen and pelvis
46650.72 15729.67 21913.88 Inflammatory disease of cervix, vagina and vulva
44976.08 10526.32 17416.27 Disorders of function of stomach
42344.50 11901.91 17990.43 Functional digestive disorders, not elsewhere classified
40909.09 13755.98 19186.60 Symptoms involving head and neck
40430.62 13576.56 18947.37 Gastritis and duodenitis
40430.62 11124.40 16985.65 Symptoms involving respiratory system and other chest symptoms
36363.64 12320.57 17129.19 Other and unspecified disorders of back
35885.17 11842.11 16650.72 Other disorders of soft tissues
34689.00 12500.00 16937.80 Diseases of pulp and periapical tissues
34449.76 11722.49 16267.94 Other noninfectious gastroenteritis and colitis
30143.54 8253.59 12631.58 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
29186.60 5921.05 10574.16 Diseases of sebaceous glands
28708.13 6937.80 11291.87 Allergic rhinitis
26315.79 7236.84 11052.63 Pruritus and related conditions
25119.62 4784.69 8851.67 Chronic pharyngitis and nasopharyngitis
22248.80 6758.37 9856.46 Neurotic disorders
19617.22 4904.31 7846.89 Symptoms involving digestive system
18660.29 2691.39 5885.17 Pain and other symptoms associated with female genital organs
18660.29 6220.10 8708.13 Urticaria
17703.35 7057.42 9186.60 Other disorders of urethra and urinary tract
16746.41 5801.44 7990.43 Peptic ulcer, site unspecified
15071.77 4545.45 6650.72 Other diseases of upper respiratory tract
14593.30 3468.90 5693.78 Dermatophytosis
14114.83 6519.14 8038.28 Other and unspecified disorder of joint
13875.60 5143.54 6889.95 Menopausal and postmenopausal disorders
13157.89 5083.73 6698.56 Other disorders of synovium, tendon and bursa
12918.66 3468.90 5358.85 Other disorders of skin and subcutaneous tissue
12918.66 5263.16 6794.26 Osteoarthrosis and allied disorders
12679.43 4366.03 6028.71 Chronic liver disease and cirrhosis
11483.25 4844.50 6172.25 Disorders of lipoid metabolism
11244.02 2571.77 4306.22 Noninflammatory disorders of vagina
11244.02 4485.65 5837.32 Spondylosis and allied disorders
10765.55 3169.86 4689.00 Disorders of refraction and accommodation
10765.55 3767.94 5167.46 Candidiasis
10287.08 1435.41 3205.74 Other and unspecified anemias
9808.61 3050.24 4401.91 Vertiginous syndromes and other disorders of vestibular system
9569.38 2930.62 4258.37 Other disorders of cervical region
9330.14 1794.26 3301.44 Special symptoms or syndromes not elsewhere classified
9330.14 4605.26 5550.24 Essential hypertension
9330.14 3708.13 4832.54 Other diseases and conditions of the teeth and supporting structures
9330.14 4784.69 5693.78 Peripheral enthesopathies and allied syndromes
9330.14 3468.90 4641.15 Symptoms involving cardiovascular system
9090.91 2930.62 4162.68 Visual disturbances
8851.67 2751.20 3971.29 Uterine leiomyoma
8851.67 2511.96 3779.90 Diabetes mellitus
8851.67 3588.52 4641.15 Other disorders of breast
8851.67 2212.92 3540.67 Symptoms involving skin and other integumentary tissue
8612.44 299.04 1961.72 Other endocrine disorders
8133.97 2870.81 3923.44 Intervertebral disc disorders
7416.27 1674.64 2822.97 Migraine
7416.27 2870.81 3779.90 Diseases of esophagus
7416.27 2033.49 3110.05 Hemorrhage in early pregnancy
7416.27 2511.96 3492.82 Symptoms involving urinary system
7177.03 2272.73 3253.59 Asthma
6937.80 299.04 1626.79 Simple and unspecified goiter
6937.80 777.51 2009.57 Disorders of tooth development and eruption
6698.56 897.13 2057.42 Diseases of hair and hair follicles
6698.56 3588.52 4210.53 Other and unspecified arthropathies
6698.56 2272.73 3157.89 Disorders of muscle, ligament and fascia
6459.33 1375.60 2392.34 Thyrotoxicosis with or without goiter
6459.33 2093.30 2966.51 Chronic bronchitis
6459.33 1913.88 2822.97 Other diseases due to viruses and Chlamydiae
6459.33 3050.24 3732.06 Noninflammatory disorders of cervix
6220.10 1674.64 2583.73 Disorders of lacrimal system
6220.10 1375.60 2344.50 Other disorders of ear
6220.10 2033.49 2870.81 Hemorrhoids
5980.86 1076.56 2057.42 Dentofacial anomalies, including malocclusion
5980.86 2990.43 3588.52 Other disorders of bone and cartilage
5741.63 897.13 1866.03 Ovarian dysfunction
5741.63 1854.07 2631.58 Other disorders of eye
5741.63 1495.22 2344.50 Atopic dermatitis and related conditions
5502.39 1854.07 2583.73 Benign neoplasm of breast
5502.39 2990.43 3492.82 Cataract
5502.39 1255.98 2105.26 Nonsuppurative otitis media and eustachian tube disorders
5502.39 777.51 1722.49 Endometriosis
5023.92 1913.88 2535.89 Benign neoplasm of skin
5023.92 1973.68 2583.73 Cardiac dysrhythmias
5023.92 717.70 1578.95 Infertility, female
4784.69 1136.36 1866.03 Iron deficiency anemias
4784.69 1555.02 2200.96 Disorders of sweat glands
4545.45 1255.98 1913.88 Benign neoplasm of ovary
4545.45 179.43 1052.63 Other disorders of thyroid
4545.45 1315.79 1961.72 Other diseases of endocardium
4545.45 1076.56 1770.33 Chronic sinusitis
4306.22 358.85 1148.33 Acquired hypothyroidism
4306.22 1016.75 1674.64 Affective psychoses
4306.22 1495.22 2057.42 Suppurative and unspecified otitis media
4306.22 1076.56 1722.49 Viral hepatitis
4306.22 2033.49 2488.04 Gastric ulcer
4066.99 1973.68 2392.34 Hypertensive heart disease
4066.99 1674.64 2153.11 Other forms of chronic ischemic heart disease
4066.99 1555.02 2057.42 Excessive vomiting in pregnancy
4066.99 777.51 1435.41 Early or threatened labor
3827.75 1854.07 2248.80 Other disorders of eyelids
3588.52 956.94 1483.25 Other retinal disorders
3588.52 956.94 1483.25 Herpes simplex
3349.28 478.47 1052.63 Disorders of the pituitary gland and its hypothalamic control
3349.28 1136.36 1578.95 Gout
3349.28 358.85 956.94 Other dermatoses
3110.05 1076.56 1483.25 Herpes zoster
3110.05 358.85 909.09 Other and ill-defined cerebrovascular disease
3110.05 1016.75 1435.41 Benign mammary dysplasias
3110.05 598.09 1100.48 Disorders of uterus, not elsewhere classified
2870.81 1076.56 1435.41 Noninflammatory disorders of ovary, fallopian tube and broad ligament
2631.58 1136.36 1435.41 Mononeuritis of upper limb and mononeuritis multiplex
2631.58 538.28 956.94 Other disorders of intestine
2631.58 1016.75 1339.71 Other disorders of liver
2631.58 1375.60 1626.79 Normal delivery
2392.34 239.23 669.86 Thyroiditis
2392.34 179.43 622.01 Other disorders of pancreatic internal secretion
2392.34 538.28 909.09 Other current conditions in the mother classifiable elsewhere, but complicating pregnancy, childbirth, or the puerperium
2392.34 956.94 1244.02 Erythematosquamous dermatosis
2392.34 956.94 1244.02 Dermatitis due to substances taken internally
2392.34 358.85 765.55 Nonspecific abnormal results of function studies
2153.11 418.66 765.55 Other benign neoplasm of uterus
2153.11 299.04 669.86 Nontoxic nodular goiter
2153.11 239.23 622.01 Disorders of the globe
2153.11 358.85 717.70 Chronic disease of tonsils and adenoids
2153.11 1255.98 1435.41 Duodenal ulcer
2153.11 717.70 1004.78 Diffuse diseases of connective tissue
2153.11 179.43 574.16 Rheumatoid arthritis and other inflammatory polyarthropathies
1913.88 299.04 622.01 Obesity and other hyperalimentation
1913.88 1016.75 1196.17 Nerve root and plexus disorders
1913.88 59.81 430.62 Mononeuritis of lower limb
1913.88 239.23 574.16 Hereditary and idiopathic peripheral neuropathy
1913.88 478.47 765.55 Glaucoma
1913.88 418.66 717.70 Ill-defined descriptions and complications of heart disease
1913.88 538.28 813.40 Other disorders of bladder
1913.88 956.94 1148.33 Other disorders of female genital organs
1913.88 358.85 669.86 Other complications of pregnancy, not elsewhere classified
1913.88 1136.36 1291.87 Other hypertrophic and atrophic conditions of skin
1913.88 478.47 765.55 Internal derangement of knee
1674.64 897.13 1052.63 Other benign neoplasm of connective and other soft tissue
1674.64 1076.56 1196.17 Physiological malfunction arising from mental factors
1674.64 598.09 813.40 Angina pectoris
1674.64 358.85 622.01 Diseases of the salivary glands
1674.64 956.94 1100.48 Regional enteritis
1674.64 358.85 622.01 Psoriasis and similar disorders
1674.64 717.70 909.09 Other derangement of joint
1435.41 1016.75 1100.48 Neoplasm of unspecified nature
1435.41 239.23 478.47 Other and unspecified disorders of metabolism
1435.41 179.43 430.62 Adjustment reaction
1435.41 538.28 717.70 Hearing loss
1435.41 358.85 574.16 Erythematous conditions
1435.41 239.23 478.47 Curvature of spine
1196.17 59.81 287.08 Disorders of adrenal glands
1196.17 239.23 430.62 Other diseases of blood and blood-forming organs
1196.17 478.47 622.01 Depressive disorder, not elsewhere classified
1196.17 299.04 478.47 Group B streptococcus infections of unspecified site
1196.17 179.43 382.78 Hypotension
1196.17 239.23 430.62 Ectopic pregnancy
1196.17 598.09 717.70 Dermatomycosis, other and unspecified
1196.17 119.62 334.93 Acariasis
956.94 179.43 334.93 Benign neoplasm of lip, oral cavity and pharynx
956.94 179.43 334.93 Schizophrenic disorders
956.94 179.43 334.93 Acute reaction to stress
956.94 119.62 287.08 Facial nerve disorders
956.94 358.85 478.47 Chickenpox
956.94 478.47 574.16 Heart failure
956.94 119.62 287.08 Other disorders of circulatory system
956.94 299.04 430.62 Other diseases of respiratory system
956.94 179.43 334.93 Diseases and other conditions of the tongue
956.94 239.23 382.78 Specific diseases due to Coxsackie virus
956.94 418.66 526.32 Antepartum hemorrhage, abruptio placentae, and placenta previa
956.94 418.66 526.32 Ankylosing spondylitis and other inflammatory spondylopathies
956.94 358.85 478.47 Other acquired deformity
956.94 119.62 287.08 Bulbus cordis anomalies and anomalies of cardiac septal closure
956.94 59.81 239.23 Congenital anomalies of the integument
956.94 239.23 382.78 Other perinatal jaundice
717.70 717.70 717.70 Benign neoplasm of other parts of digestive system
717.70 239.23 334.93 Hemangioma and lymphangioma, any site
717.70 239.23 334.93 Benign neoplasm of other and unspecified sites
717.70 119.62 239.23 Hereditary hemolytic anemias
717.70 239.23 334.93 Other extrapyramidal disease and abnormal movement disorders
717.70 179.43 287.08 Inflammatory and toxic neuropathy
717.70 358.85 430.62 Corneal opacity and other disorders of cornea
717.70 239.23 334.93 Coronary occlusion without myocardial infarction
717.70 59.81 191.39 Acute, but ill-defined, cerebrovascular disease
717.70 179.43 287.08 Deviated nasal septum
717.70 299.04 382.78 Nasal polyps
717.70 358.85 430.62 Chronic laryngitis and laryngotracheitis
717.70 299.04 382.78 Gastrojejunal ulcer
717.70 239.23 334.93 Nephritis and nephropathy, not specified as acute or chronic
717.70 478.47 526.32 Chronic renal failure
717.70 239.23 334.93 Hydronephrosis
717.70 119.62 239.23 Viral and chlamydial infection in conditions classified elsewhere and of unspecified site
717.70 179.43 287.08 Other and unspecified complications of the puerperium, not elsewhere classified
717.70 59.81 191.39 Acquired deformities of toe
717.70 418.66 478.47 Symptoms involving nervous and musculoskeletal systems
478.47 299.04 334.93 Malignant neoplasm of female breast
478.47 59.81 143.54 Malignant neoplasm of body of uterus
478.47 59.81 143.54 Lipoma
478.47 239.23 287.08 Neoplasm of uncertain behavior of other and unspecified sites and tissues
478.47 179.43 239.23 Kwashiorkor
478.47 179.43 239.23 Personality disorders
478.47 59.81 143.54 Hemiplegia and hemiparesis
478.47 179.43 239.23 Retinal detachments and defects
478.47 119.62 191.39 Hypertensive renal disease
478.47 299.04 334.93 Late effects of cerebrovascular disease
478.47 418.66 430.62 Other peripheral vascular disease
478.47 119.62 191.39 Chronic airways obstruction, not elsewhere classified
478.47 59.81 143.54 Inguinal hernia
478.47 239.23 287.08 Anal fissure and fistula
478.47 59.81 143.54 Acute and subacute necrosis of liver
478.47 358.85 382.78 Chronic glomerulonephritis
478.47 239.23 287.08 Disorders resulting from impaired renal function
478.47 179.43 239.23 Noninflammatory disorders of vulva and perineum
478.47 119.62 191.39 Hypertension complicating pregnancy, childbirth, and the puerperium
478.47 59.81 143.54 Infectious and parsitic conditions in the mother classifiable elsewhere, but complicating pregnancy, childbirth, or the puerperium
478.47 59.81 143.54 Malposition and malpresentation of fetus
478.47 239.23 287.08 Other complications of labor and delivery, not elsewhere classified
478.47 179.43 239.23 Corns and callosities
478.47 478.47 478.47 Other congenital musculoskeletal anomalies
478.47 299.04 334.93 Nonspecific findings on examination of blood
478.47 478.47 478.47 Nonspecific findings on examination of urine
478.47 239.23 287.08 Other ill-defined and unknown causes of morbidity and mortality
239.23 119.62 143.54 Malignant neoplasm of colon
239.23 119.62 143.54 Malignant neoplasm of rectum, rectosigmoid junction, and anus
239.23 59.81 95.69 Malignant neoplasm of ovary and other uterine adnexa
239.23 59.81 95.69 Benign neoplasm of bone and articular cartilage
239.23 239.23 239.23 Benign neoplasm of thyroid glands
239.23 59.81 95.69 Benign neoplasm of other endocrine glands and related structures
239.23 299.04 287.08 Carcinoma in situ of breast and genitourinary system
239.23 59.81 95.69 Neoplasm of uncertain behavior of digestive and respiratory systems
239.23 59.81 95.69 Neoplasm of uncertain behavior of genitourinary organs
239.23 119.62 143.54 Disorders of parathyroid gland
239.23 179.43 191.39 Pulmonary tuberculosis
239.23 59.81 95.69 Disorders of carbohydrate transport and metabolism
239.23 179.43 191.39 Other deficiency anemias
239.23 59.81 95.69 Aplastic anemia
239.23 119.62 143.54 Purpura and other hemorrhagic conditions
239.23 59.81 95.69 Diseases of white blood cells
239.23 119.62 143.54 Senile and presenile organic psychotic conditions
239.23 59.81 95.69 Paranoid states
239.23 119.62 143.54 Other nonorganic psychoses
239.23 119.62 143.54 Specific nonpsychotic mental disorder due to organic brain damage
239.23 59.81 95.69 Psychic factors associated with diseases classified elsewhere
239.23 119.62 143.54 Parkinson's disease
239.23 59.81 95.69 Disorders of the autonomic nervous system
239.23 59.81 95.69 Infantile cerebral palsy
239.23 59.81 95.69 Myoneural disorders
239.23 179.43 191.39 Disorders of iris and ciliary body
239.23 119.62 143.54 Disorders of optic nerve and visual pathways
239.23 179.43 191.39 Rheumatic diseases of mitral valve
239.23 119.62 143.54 Other rheumatic heart disease
239.23 179.43 191.39 Secondary hypertension
239.23 59.81 95.69 Old myocardial infarction
239.23 59.81 95.69 Acute pulmonary heart disease
239.23 299.04 287.08 Atherosclerosis
239.23 119.62 143.54 Arterial embolism and thrombosis
239.23 59.81 95.69 Polyarteritis nodosa and allied conditions
239.23 179.43 191.39 Other disorders of arteries and arterioles
239.23 59.81 95.69 Diseases of capillaries
239.23 59.81 95.69 Phlebitis and thrombophlebitis
239.23 59.81 95.69 Other venous embolism and thrombosis
239.23 59.81 95.69 Varicose veins of lower extremities
239.23 59.81 95.69 Postinflammatory pulmonary fibrosis
239.23 179.43 191.39 Diseases of the jaws
239.23 179.43 191.39 Other disorders of stomach and duodenum
239.23 59.81 95.69 Ulcerative colitis
239.23 239.23 239.23 Renal failure, unspecified
239.23 179.43 191.39 Genital prolapse
239.23 358.85 334.93 Other fetal and placental problems affecting management of mother
239.23 59.81 95.69 Other indications for care or intervention related to labor and delivery, not elsewhere classified
239.23 59.81 95.69 Bullous dermatoses
239.23 119.62 143.54 Chronic ulcer of skin
239.23 59.81 95.69 Crystal arthropathies
239.23 119.62 143.54 Other acquired deformities of limbs
239.23 119.62 143.54 Other congenital anomalies of heart
239.23 59.81 95.69 Congenital anomalies of urinary system
239.23 59.81 95.69 Nonspecific abnormal histological and immunological findings
239.23 59.81 95.69 Other mycoses
239.23 59.81 95.69 Other and unspecified infectious and parasitic diseases
239.23 119.62 143.54 Late effects of tuberculosis