The Egocentric Comorbidity Network on Specific delays in development


Disease Info.
ICD-9: 315
Disease ID: 255
Disease Name: Specific delays in development
Descriptives of the sampled nested cases-control dataset
Total individual= 13170
Case:Control = 2634 : 10536 ( 1 : 4 )
No. of control with zero baseline= 8924
No. of select variables= 294
Messages in th clogit procedure
WARN: Loglik converged before variable 206,210 ; coefficient may be infinite.
Fitted coefficients in conditional logistic model (p<0.05 only)
*Progression links allowed are marked in red
coef exp(coef) se(coef) z Pr(>|z|) name sig
4.568 96.322 1.781 2.564 0.010 Coronary occlusion without myocardial infarction **
3.937 51.245 1.416 2.780 0.005 Late effects of tuberculosis **
1.416 4.120 0.558 2.539 0.011 Other nutritional deficiencies *
1.175 3.238 0.307 3.830 0.000 Other congenital musculoskeletal anomalies ***
1.161 3.192 0.559 2.076 0.038 Bullous dermatoses *
1.018 2.768 0.494 2.061 0.039 Simple and unspecified goiter *
0.863 2.371 0.188 4.597 0.000 Other retinal disorders ***
0.781 2.184 0.226 3.454 0.001 Other congenital anomalies of upper alimentary tract ***
0.775 2.171 0.308 2.513 0.012 Disorders of the pituitary gland and its hypothalamic control *
0.736 2.088 0.145 5.075 0.000 Infantile cerebral palsy ***
0.683 1.980 0.237 2.883 0.004 Cleft palate and cleft lip **
0.660 1.934 0.076 8.647 0.000 Hyperkinetic syndrome of childhood ***
0.654 1.924 0.282 2.316 0.021 Other and unspecified congenital anomalies *
0.650 1.916 0.171 3.807 0.000 Physiological malfunction arising from mental factors ***
0.638 1.893 0.163 3.924 0.000 Unspecified mental retardation ***
0.637 1.891 0.262 2.427 0.015 Diseases of the salivary glands *
0.600 1.822 0.218 2.751 0.006 Other congenital anomalies of circulatory system **
0.590 1.804 0.222 2.658 0.008 Infections specific to the perinatal period **
0.574 1.775 0.161 3.562 0.000 Bulbus cordis anomalies and anomalies of cardiac septal closure ***
0.572 1.772 0.129 4.418 0.000 Hearing loss ***
0.570 1.769 0.065 8.752 0.000 Diseases of hard tissues of teeth ***
0.569 1.767 0.148 3.848 0.000 Symptoms involving nervous and musculoskeletal systems ***
0.534 1.706 0.172 3.099 0.002 Other conditions of brain **
0.527 1.695 0.225 2.348 0.019 Other disorders of cervical region *
0.513 1.671 0.058 8.838 0.000 Contact dermatitis and other eczema ***
0.492 1.636 0.123 3.993 0.000 Epilepsy ***
0.453 1.574 0.176 2.579 0.010 Disorders relating to short gestation and unspecified low birthweight **
0.435 1.545 0.153 2.844 0.004 Disturbance of emotions specific to childhood and adolescence **
0.425 1.529 0.056 7.583 0.000 Other noninfectious gastroenteritis and colitis ***
0.409 1.506 0.057 7.202 0.000 Functional digestive disorders, not elsewhere classified ***
0.402 1.494 0.177 2.272 0.023 Other congenital anomalies of nervous system *
0.337 1.401 0.058 5.856 0.000 General symptoms ***
0.312 1.367 0.064 4.846 0.000 Symptoms involving head and neck ***
0.258 1.294 0.126 2.039 0.041 Chickenpox *
0.251 1.285 0.062 4.014 0.000 Symptoms involving digestive system ***
0.226 1.253 0.067 3.342 0.001 Atopic dermatitis and related conditions ***
0.166 1.181 0.063 2.635 0.008 Suppurative and unspecified otitis media **
0.162 1.176 0.063 2.575 0.010 Specific diseases due to Coxsackie virus **
0.140 1.151 0.063 2.243 0.025 Gastritis and duodenitis *
-0.311 0.733 0.136 -2.280 0.023 Disorders of sweat glands *
-5.405 0.004 2.699 -2.002 0.045 Normal delivery *
Age distribution of cases
Prevalence of exposure in the dataset per 100,000
*marked green when case > control
case control overall name
42179.20 6805.24 13880.03 Diseases of hard tissues of teeth
39331.81 4536.83 11495.82 Contact dermatitis and other eczema
38192.86 4394.46 11154.14 General symptoms
35193.62 3976.84 10220.20 Functional digestive disorders, not elsewhere classified
29498.86 4119.21 9195.14 Other noninfectious gastroenteritis and colitis
25246.77 2875.85 7350.04 Allergic rhinitis
24487.47 2534.17 6924.83 Symptoms involving digestive system
24259.68 3122.63 7350.04 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
23044.80 2686.03 6757.78 Specific diseases due to Coxsackie virus
22817.01 3350.42 7243.74 Gastritis and duodenitis
22589.22 2648.06 6636.29 Suppurative and unspecified otitis media
22399.39 3407.37 7205.77 Other symptoms involving abdomen and pelvis
20842.82 3056.19 6613.52 Symptoms involving respiratory system and other chest symptoms
20425.21 1945.71 5641.61 Symptoms involving head and neck
19552.01 2353.83 5793.47 Disorders of refraction and accommodation
17919.51 2268.41 5398.63 Disorders of function of stomach
17160.21 1509.11 4639.33 Atopic dermatitis and related conditions
16552.77 2989.75 5702.35 Diseases of pulp and periapical tissues
15641.61 2799.92 5368.26 Gingival and periodontal diseases
14616.55 1727.41 4305.24 Asthma
13287.78 1784.36 4085.04 Urticaria
12680.33 47.46 2574.03 Hyperkinetic syndrome of childhood
10478.36 1338.27 3166.29 Chronic pharyngitis and nasopharyngitis
10402.43 1717.92 3454.82 Other diseases and conditions of the teeth and supporting structures
10174.64 1214.88 3006.83 Other disorders of urethra and urinary tract
10136.67 1262.34 3037.21 Other diseases of upper respiratory tract
8845.86 1271.83 2786.64 Pruritus and related conditions
8276.39 901.67 2376.61 Nonsuppurative otitis media and eustachian tube disorders
6719.82 835.23 2012.15 Visual disturbances
6036.45 730.83 1791.95 Disorders of tooth development and eruption
5201.21 94.91 1116.17 Epilepsy
4631.74 816.25 1579.35 Other disorders of skin and subcutaneous tissue
4176.16 18.98 850.42 Infantile cerebral palsy
4138.19 474.56 1207.29 Candidiasis
4100.23 351.18 1100.99 Chronic sinusitis
4024.30 85.42 873.20 Hearing loss
4024.30 512.53 1214.88 Viral and chlamydial infection in conditions classified elsewhere and of unspecified site
3796.51 360.67 1047.84 Herpes simplex
3416.86 417.62 1017.46 Chickenpox
3265.00 939.64 1404.71 Inflammatory disease of cervix, vagina and vulva
3265.00 996.58 1450.27 Other disorders of soft tissues
3189.07 75.93 698.56 Disorders relating to short gestation and unspecified low birthweight
3151.10 436.60 979.50 Disorders of sweat glands
3075.17 161.35 744.12 Strabismus and other disorders of binocular eye movements
2999.24 47.46 637.81 Bulbus cordis anomalies and anomalies of cardiac septal closure
2961.28 47.46 630.22 Symptoms involving nervous and musculoskeletal systems
2923.31 104.40 668.19 Other congenital anomalies of heart
2847.38 455.58 933.94 Diseases of sebaceous glands
2619.59 9.49 531.51 Unspecified mental retardation
2581.62 18.98 531.51 Disturbance of emotions specific to childhood and adolescence
2505.69 189.83 653.00 Special symptoms or syndromes not elsewhere classified
2505.69 522.02 918.75 Dermatophytosis
2467.73 389.14 804.86 Neurotic disorders
2391.80 322.70 736.52 Symptoms involving skin and other integumentary tissue
2353.83 9.49 478.36 Other conditions of brain
2353.83 104.40 554.29 Other retinal disorders
2277.90 389.14 766.89 Other diseases due to viruses and Chlamydiae
2277.90 47.46 493.55 Other congenital anomalies of nervous system
2126.04 379.65 728.93 Chronic bronchitis
2126.04 901.67 1146.55 Disorders of menstruation and other abnormal bleeding from female genital tract
2088.08 85.42 485.95 Physiological malfunction arising from mental factors
2088.08 265.76 630.22 Other disorders of eyelids
2088.08 522.02 835.23 Other and unspecified disorder of joint
2012.15 208.81 569.48 Other perinatal jaundice
1936.22 180.33 531.51 Other disorders of ear
1936.22 294.23 622.63 Symptoms involving cardiovascular system
1632.50 768.79 941.53 Other and unspecified disorders of back
1594.53 199.32 478.36 Group B streptococcus infections of unspecified site
1556.57 322.70 569.48 Regional enteritis
1480.64 151.86 417.62 Other viral exanthemata
1480.64 208.81 463.17 Dermatitis due to substances taken internally
1480.64 47.46 334.09 Other congenital anomalies of circulatory system
1480.64 265.76 508.73 Symptoms involving urinary system
1442.67 246.77 485.95 Other disorders of cervical region
1328.78 180.33 410.02 Other diseases of respiratory system
1290.81 37.97 288.53 Certain congenital musculoskeletal deformities
1252.85 104.40 334.09 Diseases of hair and hair follicles
1176.92 417.62 569.48 Peripheral enthesopathies and allied syndromes
1176.92 379.65 539.10 Other disorders of synovium, tendon and bursa
1176.92 37.97 265.76 Curvature of spine
1176.92 28.47 258.16 Cleft palate and cleft lip
1176.92 37.97 265.76 Other congenital anomalies of upper alimentary tract
1138.95 132.88 334.09 Other endocrine disorders
1138.95 132.88 334.09 Disorders of lacrimal system
1100.99 142.37 334.09 Other and unspecified anemias
1063.02 559.98 660.59 Osteoarthrosis and allied disorders
1063.02 75.93 273.35 Infections specific to the perinatal period
1025.06 512.53 615.03 Peptic ulcer, site unspecified
987.09 170.84 334.09 Other disorders of eye
987.09 75.93 258.16 Erythematous conditions
949.13 370.16 485.95 Disorders of lipoid metabolism
911.16 474.56 561.88 Essential hypertension
911.16 170.84 318.91 Diseases of esophagus
911.16 123.39 280.94 Inguinal hernia
873.20 322.70 432.80 Vertiginous syndromes and other disorders of vestibular system
873.20 132.88 280.94 Erythematosquamous dermatosis
873.20 18.98 189.83 Other and unspecified congenital anomalies
835.23 218.30 341.69 Benign neoplasm of skin
835.23 9.49 174.64 Other acquired deformities of limbs
797.27 28.47 182.23 Congenital hypothyroidism
797.27 199.32 318.91 Cardiac dysrhythmias
759.30 189.83 303.72 Diabetes mellitus
759.30 104.40 235.38 Diseases of the salivary glands
759.30 208.81 318.91 Chronic liver disease and cirrhosis
759.30 75.93 212.60 Other ill-defined and unknown causes of morbidity and mortality
721.34 18.98 159.45 Adjustment reaction
721.34 170.84 280.94 Disorders of muscle, ligament and fascia
721.34 9.49 151.86 Other congenital musculoskeletal anomalies
683.37 9.49 144.27 Other diseases of lung
683.37 104.40 220.20 Dentofacial anomalies, including malocclusion
683.37 9.49 144.27 Other respiratory conditions of fetus and newborn
683.37 37.97 167.05 Other and ill-defined conditions originating in the perinatal period
683.37 37.97 167.05 Dermatomycosis, other and unspecified
645.41 341.69 402.43 Cataract
645.41 151.86 250.57 Chronic disease of tonsils and adenoids
645.41 18.98 144.27 Other congenital anomalies of limbs
645.41 56.95 174.64 Other intestinal helminthiases
607.44 37.97 151.86 Disorders of the pituitary gland and its hypothalamic control
607.44 56.95 167.05 Disorders of the globe
607.44 104.40 205.01 Heart failure
607.44 237.28 311.31 Other disorders of breast
569.48 75.93 174.64 Glaucoma
569.48 275.25 334.09 Hypertensive heart disease
569.48 37.97 144.27 Late effects of cerebrovascular disease
569.48 9.49 121.49 Other disorders of kidney and ureter
569.48 284.74 341.69 Other and unspecified arthropathies
569.48 37.97 144.27 Other derangement of joint
569.48 180.33 258.16 Intervertebral disc disorders
531.51 9.49 113.90 Disturbance of conduct not elsewhere classified
531.51 398.63 425.21 Spondylosis and allied disorders
531.51 75.93 167.05 Acariasis
493.55 227.79 280.94 Other forms of chronic ischemic heart disease
493.55 47.46 136.67 Other diseases of endocardium
493.55 28.47 121.49 Ill-defined descriptions and complications of heart disease
493.55 37.97 129.08 Hydronephrosis
493.55 218.30 273.35 Menopausal and postmenopausal disorders
493.55 94.91 174.64 Psoriasis and similar disorders
455.58 9.49 98.71 Hemiplegia and hemiparesis
455.58 37.97 121.49 Other disorders of middle ear and mastoid
455.58 256.26 296.13 Other disorders of bone and cartilage
417.62 18.98 98.71 Other benign neoplasm of connective and other soft tissue
417.62 37.97 113.90 Simple and unspecified goiter
417.62 9.49 91.12 Congenital anomalies of eye
379.65 37.97 106.30 Other disorders of thyroid
379.65 47.46 113.90 Corneal opacity and other disorders of cornea
379.65 142.37 189.83 Noninflammatory disorders of vagina
379.65 94.91 151.86 Other hypertrophic and atrophic conditions of skin
341.69 28.47 91.12 Obesity and other hyperalimentation
341.69 9.49 75.93 Schizophrenic disorders
341.69 66.44 121.49 Herpes zoster
341.69 85.42 136.67 Other disorders of intestine
341.69 208.81 235.38 Pain and other symptoms associated with female genital organs
341.69 113.90 159.45 Other dermatoses
341.69 9.49 75.93 Congenital anomalies of ear, face and neck
341.69 9.49 75.93 Fetal and neonatal haemorrhage
303.72 28.47 83.52 Other and unspecified protein-calorie malnutrition
303.72 123.39 159.45 Gout
303.72 56.95 106.30 Iron deficiency anemias
303.72 18.98 75.93 Acute reaction to stress
303.72 113.90 151.86 Migraine
303.72 56.95 106.30 Relapsing fever
265.76 28.47 75.93 Acquired hypothyroidism
265.76 28.47 75.93 Thiamine and niacin deficiency states
265.76 94.91 129.08 Streptococcal sore throat and scarlet fever
265.76 9.49 60.74 Meningitis of unspecified cause
265.76 28.47 75.93 Inflammatory and toxic neuropathy
265.76 75.93 113.90 Viral hepatitis
265.76 56.95 98.71 Gastrojejunal ulcer
265.76 56.95 98.71 Other disorders of bladder
265.76 104.40 136.67 Noninflammatory disorders of cervix
265.76 37.97 83.52 Internal derangement of knee
265.76 37.97 83.52 Other mycoses
227.79 85.42 113.90 Neoplasm of unspecified nature
227.79 75.93 106.30 Thyrotoxicosis with or without goiter
227.79 18.98 60.74 Purpura and other hemorrhagic conditions
227.79 66.44 98.71 Affective psychoses
227.79 9.49 53.15 Other extrapyramidal disease and abnormal movement disorders
227.79 9.49 53.15 Muscular dystrophies and other myopathies
227.79 18.98 60.74 Disorders of optic nerve and visual pathways
227.79 47.46 83.52 Chronic laryngitis and laryngotracheitis
227.79 94.91 121.49 Chronic airways obstruction, not elsewhere classified
227.79 9.49 53.15 Pneumonitis due to solids and liquids
227.79 9.49 53.15 Diseases of the jaws
227.79 28.47 68.34 Diseases and other conditions of the tongue
227.79 208.81 212.60 Gastric ulcer
227.79 9.49 53.15 Anal fissure and fistula
227.79 9.49 53.15 Congenital anomalies of urinary system
189.83 28.47 60.74 Benign neoplasm of breast
189.83 28.47 60.74 Hemangioma and lymphangioma, any site
189.83 37.97 68.34 Deficiency of B -complex components
189.83 37.97 68.34 Disorders involving the immune mechanism
189.83 37.97 68.34 Senile and presenile organic psychotic conditions
189.83 9.49 45.56 Parkinson's disease
189.83 132.88 144.27 Nerve root and plexus disorders
189.83 66.44 91.12 Mononeuritis of lower limb
189.83 9.49 45.56 Chronic pulmonary heart disease
189.83 56.95 83.52 Other and ill-defined cerebrovascular disease
189.83 18.98 53.15 Other peripheral vascular disease
189.83 37.97 68.34 Other disorders of stomach and duodenum
189.83 9.49 45.56 Other hernia of abdominal cavity without mention of obstruction or gangrene
189.83 37.97 68.34 Intestinal malabsorption
189.83 9.49 45.56 Other and unspecified helminthiases
151.86 28.47 53.15 Disorders of adrenal glands
151.86 9.49 37.97 Other nutritional deficiencies
151.86 9.49 37.97 Other diseases of blood and blood-forming organs
151.86 47.46 68.34 Disorders of iris and ciliary body
151.86 123.39 129.08 Angina pectoris
151.86 94.91 106.30 Hemorrhoids
151.86 151.86 151.86 Duodenal ulcer
151.86 9.49 37.97 Ulcerative colitis
151.86 37.97 60.74 Other disorders of liver
151.86 28.47 53.15 Chronic glomerulonephritis
151.86 18.98 45.56 Disorders resulting from impaired renal function
151.86 47.46 68.34 Endometriosis
151.86 56.95 75.93 Early or threatened labor
151.86 9.49 37.97 Bullous dermatoses
151.86 18.98 45.56 Diseases of nail
151.86 28.47 53.15 Other acquired deformity
151.86 18.98 45.56 Endocrine and metabolic disturbances specific to the fetus and newborn
151.86 75.93 91.12 Nonspecific findings on examination of blood
151.86 18.98 45.56 Nonspecific findings on examination of urine
151.86 18.98 45.56 Nonspecific abnormal results of function studies
151.86 18.98 45.56 Other nonspecific abnormal findings
113.90 85.42 91.12 Uterine leiomyoma
113.90 18.98 37.97 Benign neoplasm of other and unspecified sites
113.90 56.95 68.34 Ovarian dysfunction
113.90 18.98 37.97 Hereditary hemolytic anemias
113.90 18.98 37.97 Depressive disorder, not elsewhere classified
113.90 18.98 37.97 Blindness and low vision
113.90 9.49 30.37 Other disorders of tympanic membrane
113.90 37.97 53.15 Other disorders of circulatory system
113.90 56.95 68.34 Deviated nasal septum
113.90 9.49 30.37 Emphysema
113.90 18.98 37.97 Chronic renal failure
113.90 47.46 60.74 Benign mammary dysplasias
113.90 18.98 37.97 Disorders of uterus, not elsewhere classified
113.90 18.98 37.97 Ankylosing spondylitis and other inflammatory spondylopathies
75.93 28.47 37.97 Benign neoplasm of other parts of digestive system
75.93 28.47 37.97 Lipoma
75.93 56.95 60.74 Benign neoplasm of ovary
75.93 18.98 30.37 Nontoxic nodular goiter
75.93 9.49 22.78 Thyroiditis
75.93 9.49 22.78 Other disorders of pancreatic internal secretion
75.93 9.49 22.78 Disorders of mineral metabolism
75.93 18.98 30.37 Other deficiency anemias
75.93 37.97 45.56 Mononeuritis of upper limb and mononeuritis multiplex
75.93 28.47 37.97 Hereditary and idiopathic peripheral neuropathy
75.93 9.49 22.78 Cowpox and paravaccinia
75.93 9.49 22.78 Hypertensive heart and renal disease
75.93 9.49 22.78 Secondary hypertension
75.93 9.49 22.78 Coronary occlusion without myocardial infarction
75.93 28.47 37.97 Acute, but ill-defined, cerebrovascular disease
75.93 9.49 22.78 Measles
75.93 28.47 37.97 Arterial embolism and thrombosis
75.93 28.47 37.97 Other disorders of arteries and arterioles
75.93 18.98 30.37 Noninfectious disorders of lymphatic channels
75.93 18.98 30.37 Hypotension
75.93 9.49 22.78 Genital prolapse
75.93 132.88 121.49 Hemorrhage in early pregnancy
75.93 9.49 22.78 Antepartum hemorrhage, abruptio placentae, and placenta previa
75.93 66.44 68.34 Excessive vomiting in pregnancy
75.93 18.98 30.37 Other current conditions in the mother classifiable elsewhere, but complicating pregnancy, childbirth, or the puerperium
75.93 9.49 22.78 Other fetal and placental problems affecting management of mother
75.93 28.47 37.97 Lichen
75.93 37.97 45.56 Corns and callosities
75.93 47.46 53.15 Rheumatoid arthritis and other inflammatory polyarthropathies
75.93 9.49 22.78 Intestinal parasitism, unspecified
37.97 18.98 22.78 Malignant neoplasm of cervix uteri
37.97 28.47 30.37 Benign neoplasm of lip, oral cavity and pharynx
37.97 37.97 37.97 Other benign neoplasm of uterus
37.97 18.98 22.78 Benign neoplasm of brain and other parts of nervous system
37.97 9.49 15.19 Disorders of parathyroid gland
37.97 9.49 15.19 Vitamin D deficiency
37.97 9.49 15.19 Other cerebral degenerations
37.97 9.49 15.19 Disorders of the autonomic nervous system
37.97 18.98 22.78 Trigeminal nerve disorders
37.97 9.49 15.19 Mastoiditis and related conditions
37.97 18.98 22.78 Rheumatic diseases of mitral valve
37.97 18.98 22.78 Hypertensive renal disease
37.97 9.49 15.19 Cardiomyopathy
37.97 18.98 22.78 Varicose veins of lower extremities
37.97 28.47 30.37 Nasal polyps
37.97 28.47 30.37 Bronchiectasis
37.97 18.98 22.78 Mumps
37.97 9.49 15.19 Liver abscess and sequelae of chronic liver disease
37.97 28.47 30.37 Infectious mononucleosis
37.97 56.95 53.15 Noninflammatory disorders of ovary, fallopian tube and broad ligament
37.97 18.98 22.78 Other complications of pregnancy, not elsewhere classified
37.97 104.40 91.12 Normal delivery
37.97 28.47 30.37 Other and unspecified complications of the puerperium, not elsewhere classified
37.97 9.49 15.19 Chronic ulcer of skin
37.97 37.97 37.97 Diffuse diseases of connective tissue
37.97 9.49 15.19 Coccidioidomycosis
37.97 9.49 15.19 Late effects of tuberculosis